Tyrphostin AG 1296

CAS No. 146535-11-7

Tyrphostin AG 1296 ( 6,7-Dimethoxy-3-phenylquinoxaline )

Catalog No. M17312 CAS No. 146535-11-7

Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 80 In Stock
10MG 138 In Stock
25MG 285 In Stock
50MG 441 In Stock
100MG 651 In Stock
500MG 1368 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tyrphostin AG 1296
  • Note
    Research use only, not for human use.
  • Brief Description
    Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.
  • Description
    6,7-Dimethoxy-3-phenylquinoxaline is an ATP-competitive inhibitor of receptor kinase.
  • Synonyms
    6,7-Dimethoxy-3-phenylquinoxaline
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    PDGFR
  • Research Area
    Cardiovascular Disease|Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    146535-11-7
  • Formula Weight
    266.29
  • Molecular Formula
    C16H14N2O2
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    COc1cc2nc(cnc2cc1OC)c3ccccc3
  • Chemical Name
    6,7-Dimethoxy-3-phenylquinoxaline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kovalenko M, et al. Cancer Res, 1994, 54(23), 6106-6114.
molnova catalog
related products
  • Chrysophanic Acid

    Extracted from Rheum palmatum L.;Suitability:Boiling ethanol,benzene,chloroform,ether,acetic acid and acetone.

  • EGFR Inhibitor

    EGFR inhibitor is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.

  • AZD8931 diFuMaric ac...

    AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).AZD8931 significantly suppressed cell growth of IBC cells and induced apoptosis of human IBC cells in vitro.AZD8931 monotherapy inhibited xenograft growth.